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Published 22 Apr 2025

Article by

Jona Tarlengco

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4 min read

What is a Laboratory Safety Checklist?

A laboratory safety checklist, or lab safety checklist, is utilized by lab supervisors and safety officers to identify and minimize chemical, biological, physical and radioactive hazards present in laboratory facilities at schools and hospitals, among others. It helps ensure that the laboratory complies with environmental standards to prevent overexposure to hazardous chemicals, injuries and respiratory-related illnesses or fatalities.

Types of Laboratory Safety Hazards

For clinical, industrial, and academic laboratory personnel, the laboratory environment can be a hazardous place to work. According to the Occupational Health and Safety Administration (OSHA), here are the different types of hazards workers can encounter while in laboratories:

Chemical Hazards – Laboratory chemicals like formaldehyde can include cancer-causing agents (carcinogens), toxins (e.g., those affecting the liver, kidney, and nervous system), irritants, corrosives, sensitizers, as well as agents that act on the blood system or damage the lungs, skin, eyes, or mucous membranes. Air contaminants such as toluene, xylene, and acrylamide require even more specific hazard communication (HAZCOM) and Material Safety Data Sheets (MSDSs).

Biological Hazards – Many lab workers are regularly exposed to biological hazards like blood, body fluids, tissue samples, cadavers, lab animals, and other personnel. These regulated agents—such as viruses, bacteria, fungi, prions, and toxins—can lead to infections, zoonotic and foodborne diseases, Legionnaires’ Disease, and mold-related respiratory issues.

Physical Hazards – Common physical hazards include ergonomic issues, ionizing and non-ionizing radiation, and noise. Repetitive tasks like pipetting, using microscopes, and operating microtomes often cause ergonomic strain. Prolonged noise exposure can lead to stress, reduced efficiency, poor concentration, and increased lab errors.

Overlooked Laboratory Guidelines

Safety issues often arise and go unnoticed due to a lack of protocol, faulty implementation, or oversight guidelines. Most of the time employees tend to overlook simple guides that can lead to possible incidents or bigger issues. You can find below the commonly overlooked safety laboratory guidelines:

  • Dress code safety

    Wearing appropriate PPE is one of the basic requirements when working inside the laboratory. All employees must be informed of the proper dress codes to eliminate any risks of chemical contact. Employees must ensure all equipment including goggles, face shields, safety gloves, body, and respiratory protection are in good condition before entering the laboratory.

  • Laboratory waste disposal

    Hazardous wastes are classified based on their physical or chemical properties. Commonly, inappropriate disposal can cause an acute or immediate effect on employees’ health and safety. Enforcing proper waste management can eliminate potential hazards, including environmental pollution, pathogenic diseases, and chemical reactions.

  • Ergonomic safety

    Repetitive awkward postures can cause discomfort to employees that can lead to musculoskeletal disorders (MSDs), tendinitis, and carpal tunnel syndrome. Proper training on ergonomics safety can help employees maximize their laboratory efficiency and productivity.

  • Proper labels

    Labels are important elements of laboratory safety. They help in identifying chemicals, their substance, and the hazards associated with them. A proper label should have the name of the substance, its concentration, the date it was received, and the name of the person responsible for it.

  • Record of an incident

    Reporting an incident is essential to raise the organization’s awareness about the things that can go wrong so that corrective and preventative actions can be taken promptly. Keeping a record of an incident can also help both employees and business owners to have evidence in case of an accident to support their insurance claims.

4 Essential Laboratory Housekeeping and Maintenance Tips

OSHA has reinforced rules and published guidance to make laboratories increasingly safe for workers and other people involved. The following tips can help in maintaining a safe laboratory to protect employees from chemical exposures and unexpected incidents.

  • Enforce laboratory standards

    All employees must undergo proper induction and training about laboratory standards, emergency procedures, and other policies to keep them informed about the hazards in the workplace. Monitoring employees’ permissible exposure limits (PELs) protects employees from possible harm including respiratory ailments and physical injuries.

  • Keep it clean

    It is paramount to maintain laboratory cleanliness throughout the operation to secure the health and safety of employees and the property. Keep the laboratory space unobstructed and clean all spills immediately to avoid accidents.

  • Calibrate equipment

    Keep the functionality, quality, and accuracy of measuring equipment to avoid disrupting the entire experiments. Conducting regular equipment calibration helps the organization prevent accidents and damage that can lead to legal action and profit loss.

  • Remove and replace damaged items

    Maintain equipment in peak condition to prevent production hitch. Immediately report any damaged equipment either for replacement or removal to avoid unnecessary incidents and equipment malfunction.

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Article by

Jona Tarlengco

SafetyCulture Content Specialist

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